• **Avian Influenza (Bird Flu)

• USDA confirms more H5N1 avian flu in cats, other mammals The latest H5N1 confirmations in pet cats come from Kansas, Pennsylvania, Iowa, and Illinois. Lisa Schnirring

• Fatal H5N1 case reported in India's Andhra Pradesh state The source of the girl's virus might have been raw poultry, according to media reports. Lisa Schnirring

• Tests confirm H5N1 avian flu virus in recently recalled raw food for cats Cats in multiple states got sick after eating the food, which was undergoing testing in the wake of a recall. Lisa Schnirring

• **CDC Report on Avian H5N1 Flu:

• H5 Bird Flu: Current Situation
  
  *Dairy cattle:Ongoing multi-state outbreak

• *Wild Birds: H5 bird flu is widespread in wild birds worldwide

• *Poultry Flocks:Pathogenic Avian Influenza in Backyard Flocks

• *Mammals: Detections of Highly Pathogenic Avian Influenza in Mammals
  69 Confirmed Total Reported Human Cases in US 1 death

New England Journal of Medicine

• Pemivibart for Prevention of Covid-19
• Activity of Research-Grade Pemivibart against SARS-CoV-2 Sublineages
• Postacute Sequelae of SARS-CoV-2 Infection
• Long Covid Defined
• What Exactly Is Long Covid?
• Partnerships for Outbreak Response
• Nirmatrelvir–Ritonavir as Covid-19 Postexposure Prophylaxis
• Déjà Vu All Over Again
• Academic Freedom in America
• Vaccine Effectiveness against Omicron XBB.1.5 Subvariant
• Antibody Link for VITT and VITT-like Disorders
• Nirmatrelvir–Ritonavir in Outpatients with Covid-19

The Lancet Home

• In-hospital outcomes and 6-month follow-up results of patients supported with extracorporeal membrane oxygenation for COVID-19 from the second wave to the end of the pandemic (EuroECMO-COVID): a prospective, international, multicentre, observational study
• The Global Fund, Cervical Cancer, and HPV infections: what can low- and middle-income countries do to accelerate progress by 2030?
• Immunogenicity and reactogenicity of fractional vs. full booster doses of COVID-19 vaccines: a non-inferiority, randomised, double-blind, phase IV clinical trial in Brazil
• Performance of the World Health Organization (WHO) severe acute respiratory infection (SARI) case definitions in hospitalized children and youth: cross-sectional study
• Intranasal recombinant protein subunit vaccine targeting TLR3 induces respiratory tract IgA and CD8 T cell responses and protects against respiratory virus infection
• Leveraging near-real-time patient and population data to incorporate fluctuating risk of severe COVID-19: development and prospective validation of a personalised risk prediction tool
• First-Episode Psychosis incidence pre-, during, and post-COVID-19 pandemic: a six-year natural quasi-experimental study in South London
• Cost-effectiveness of screening, decolonisation and isolation strategies for carbapenem-resistant Enterobacterales and methicillin-resistant Staphylococcus aureus infections in hospitals: a sex-stratified mathematical modelling study
• Need to revisit culture isolation for detecting viraemia
• Hospitalizations for all-cause pediatric acute respiratory diseases in Alberta, Canada, before, during, and after the COVID-19 pandemic: a population-level retrospective cohort study from 2010 to 2024
• Differences in Long COVID severity by duration of illness, symptom evolution, and vaccination: a longitudinal cohort study from the INSPIRE group
• Prevalence and moderators of depression symptoms among Black individuals in Western Countries: a systematic review and meta-analysis among 1.3 million people in 421 studies
• Preparedness for infectious diseases during the Tokyo 2020 Olympic and Paralympic Games: advancing the health system beyond the games
• Emergence and spread of the SARS-CoV-2 omicron (BA.1) variant across Africa: an observational study

Jama Coronavirus Resource Center

• Outcomes Among Older Adults With and Without Restricted Access to Nirmatrelvir-Ritonavir
• Health Care Staffing Shortages and Potential National Hospital Bed Shortage
• Understanding and Addressing the US Hospital Bed Shortage

COVID-19 preprints from medRxiv Part 1

• Genetic diversity of pangolin coronaviruses reveals a key immuno-evasive substitution at spike residue 519
• Single-chain permuted proteins for dimerization-based control of protein activity and cellular processes
• Pre-Clinical Evaluation of a Novel Immunomodulator: a potential immunotherapy for coronaviral disease
• Ketamine inhibition of SARS-CoV-2 replication in astrocytes is associated with COVID-19 disease severity in a variant-dependent manner
• Modeling viral and bacterial infections in human lung organotypic systems reveals strain specific host responses
• A NanoBRET-based assay monitoring interactions in the USP18 signaling hub identifies the first cell-penetrant small molecule compromising USP18/ISG15 binding
• Divalent cations govern the activity of coronavirus nsp15
• Functional and structural characterization of a combination of pan-sarbecovirus antibodies with potent antiviral activity
• The CCR2 inflammatory pathway is a target for improving severe disease and pulmonary inflammation in experimental COVID-19
• Gut barrier integrity biomarkers are associated with increased inflammation and predict disease status in hospitalized COVID-19 patients
• Immuno-functionomics reveals geographical variation and a role for TLR8 in mRNA vaccine responses
• Biophysical fitness landscape design traps viral evolution
• Performance characteristics of the SARS-CoV-2 Isothermal Molecular Assay for point-of-care molecular diagnosis of SARS-CoV-2
• Reinfection with SARS-CoV-2 in the Omicron Era is Associated with Increased Risk of Post-Acute Sequelae of SARS-CoV-2 Infection: A RECOVER-EHR Cohort Study
• Anti-Spike IgG4 and Fc Effector Responses: The Impact of SARS-CoV-2 Vaccine Platform-Specific Priming and Immune Imprinting

Science Journals

The BMJ

• Are covid-19 tests still working?
• Will we ever know where covid-19 came from?
• Covid:19: NHS staff still struggling with “traumatic memories” of pandemic, report finds
• The vacuum of information about covid’s prevalence puts me at risk—bring back better data collection
• Covid inquiry: the flaws that led to system failure
• Interventions for the management of long covid (post-covid condition): living systematic review
• Covid-19 originated in Wuhan lab, alleges Republican congressional report
• News Long covid: 70% of 11-17 year olds recover within two years, study reports
• Scotland’s NHS performance fails to recover after covid pandemic
• US Supreme Court rejects bid to shield covid misinformation doctors from state medical board discipline
• Covid inquiry: Caring for patients without relatives’ support caused staff “strain and trauma”
• Covid inquiry: Doctors felt like “disposable commodities” during pandemic, says BMA chair
• Covid inquiry: Ethnic minority doctors felt vulnerable and afraid to raise concerns
• Covid inquiry hears harrowing evidence of effects on ICU staff
• Covid inquiry: UKHSA chief is challenged on view that evidence for FFP3 masks is “weak”

Cell Press

• Effectiveness of famotidine on the risk of poor prognosis in patients with COVID-19: A nationwide cohort study in Korea
• Perceived academic stress during a pandemic: Mediating role of coping strategies
• Extrafollicular IgD−CD27−CXCR5−CD11c− DN3 B cells infiltrate inflamed tissues in autoimmune fibrosis and in severe COVID-19
• Increased suicide rates in Mexico City during the COVID-19 pandemic outbreak: An analysis spanning from 2016 to 2021
• Sotrovimab retains activity against SARS-CoV-2 omicron variant BQ.1.1 in a non-human primate model
• Performance and satisfaction during the E-learning transition in the COVID-19 pandemic among psychiatry course medical students
• Proteomic analysis of circulating immune cells identifies cellular phenotypes associated with COVID-19 severity
• Communicating with ethnic minorities during COVID-19: An experimental test of the effect of self-, ingroup-, and intergroup-focused messages
• GRAd-COV2 vaccine provides potent and durable humoral and cellular immunity to SARS-CoV-2 in randomized placebo-controlled phase 2 trial
• Structural changes in the SARS-CoV-2 spike E406W mutant escaping a clinical monoclonal antibody cocktail
• A non-transmissible live attenuated SARS-CoV-2 vaccine
• COVID-19 associated coagulopathy: A bibliometric investigation
• The impact that myocarditis for post-acute COVID-19 syndrome may be dermatomyositis-like myocarditis: A case report
• A multimodal AI-based non-invasive COVID-19 grading framework powered by deep learning, manta ray, and fuzzy inference system from multimedia vital signs
• Examining dimensions of teachers’ digital competence: A systematic review pre- and during COVID-19

NPR Coronavirus Updates

• CDC drops its COVID-19 risk advisory for cruise ship travel
• White House press secretary Jen Psaki tests positive (again) for COVID-19
• The NFL and players' union agree to suspend COVID protocols for the 2022 season
• Disney theme parks say face masks are now optional for vaccinated visitors
• 900,000 Americans have died of COVID in 2 years of the global pandemic
• New Orleans will be the first major school district to mandate COVID vaccinations
• A shot and a swab: New Hampshire to sell at-home COVID tests in liquor outlets
• Denver children's museum closes temporarily after anger at its mask policy
• Elton John postpones Texas concerts after testing positive for COVID-19
• Kiribati and Samoa implement rare lockdowns after travelers test positive
• COVID concerns will keep NBC announcers home from the Beijing Olympics
• Starbucks drops COVID vaccine mandate after Supreme Court ruling
• Fauci says COVID-19 won't go away like smallpox, but will more likely become endemic
• In Greece, unvaccinated people ages 60 and up now face monthly fines
• Garbage and recyclables pile up as omicron takes its toll on sanitation workers

Kaiser Coronavirus (COVID-19)

• COVID Vaccine Concerns
• Childhood Vaccination Rates Continue to Decline as Trump Heads for a Second Term
• Scientists Say NIH Officials Told Them To Scrub mRNA References on Grants
• MRNA Vaccines, Once a Trump Boast, Now Face Attacks From Some in GOP
• The Covid ‘Contrarians’ Are in Power. We Still Haven’t Hashed Out Whether They Were Right.
• What a US Exit From the WHO Means for Global Health
• COVID-19 Coronavirus Tracker
• COVID-19 and Related State Data
• Racial Disparities in Premature Deaths During the Pandemic

CIDRAP COVID-19

• COVID-19 may put patients at risk for other infections for at least 1 year
• Healthcare workers with chronic condition miss more days of work due to COVID than flu, data show
• Study estimates current Moderna vaccine 53% effective against COVID hospitalization
• Ouster of top FDA vaccine official prompts concern from lawmakers, scientists
• Tests show emotional, behavioral problems in adolescents with long COVID
• Trump administration axes COVID funding for state, community health departments
• Vaccination cuts the risk of long COVID 27%, review suggests
• Study links social inequalities to long COVID
• Electronic nudges to get flu shot may unwittingly lower COVID vaccination in older adults

StatNews Coronavirus (COVID-19)

• STAT Plus: UnitedHealth gets one step closer to defeating high-profile Medicare Advantage fraud case
• A small study on Covid vaccine safety sparks an online tempest
• STAT Plus: Analysis: RFK Jr. doubles down on vaccine criticism and misinformation, imperiling key votes
• STAT Plus: The 7 big topics RFK Jr. addressed during a fiery confirmation hearing
• STAT Plus: Private emails show RFK Jr. making false claims about Covid-19 shots, linking vaccines to autism
• Trump’s initial orders reverse Biden on health care costs, protections from discrimination
• Trump orders U.S. to withdraw from World Health Organization
• A dark anniversary and the last two weeks in health news
• STAT Plus: Prognosis: Under Trump, the CDC is in big trouble, but the FDA might be OK
• STAT Plus: Rand Paul plans to investigate Covid-19 origins from his new perch leading a key committee
• How to bring more Black Americans into clinical research: Address the root causes of medical skepticism
• ‘Do no harm’ is hurting 400 million long Covid patients worldwide
• In children, Covid is tied to higher risk of type 2 diabetes
• First Opinion readers on Covid and Trump, rare diseases, and institutional neutrality
• Medicine struggles to define chronic Lyme. Long Covid has only made it harder

AP News Coronavirus (COVID-19)

• The first of 16 new F-16 fighter jets from the US land in Bulgaria
• States sue Trump administration for rescinding billions in health funding
• Brazilian prosecutor tosses ex-President Bolsonaro’s COVID-19 vaccine status case
• Asian Americans and Pacific Islanders are still targets of hatred 5 years after pandemic surge
• A handful of college coaches in March Madness stand out for their fashion choices amid a sea of casual attire
• Trump administration says it will pull back billions in COVID funding from local health departments
• Postmaster General Louis DeJoy resigns after 5 years in the position
• Up, up and spinning away. More Brazilians taking outdoor spin classes on helipads
• Viral videos of dogs called a ‘Himalayan fur goblin’ and ‘teacup werewolf’ boost adoptions
• North Carolina justices decide family can sue over unwanted COVID-19 shot
• A major new airport to serve Cambodia’s capital and boost tourism is due to open in July
• South Carolina public health chief’s confirmation hearing overshadowed by COVID anger
• In the rapidly shifting world of work, many employees are unclear what’s expected of them
• Spirit Airlines exits bankruptcy protection as travel demand slows
• 5th anniversary of COVID cancellations brings back painful memories for teams, NCAA officials

NY News Coronavirus (COVID-19)

• 15 Lessons Scientists Learned About Us When the World Stood Still

Annals of Internal Medicine(COVID-19)

• The ACP COVID-19 Resource Hub. Focused information for internists and access to the ACP Physician's Guide to COVID-19.
• ACP/Annals of Internal Medicine COVID-19 Forums. Watch the ACP/Annals virtual forum events featuring key experts discussing topics related to COVID-19.
• ACP JournalWise. This literature alert service, free to ACP members, now includes COVID topic surveillance.
• DynaMed's COVID-19 Topic Page. Also includes related summaries for treating special patient populations and more.
• COVID-19 Evidence Alerts from McMaster Plus. Summaries of the best new evidence for the care of people with suspected or confirmed COVID-19 infection.